线粒体与衰老

被引:6
作者
王怀颖
石少慧
机构
[1] 河北职工医学院生化教研室
关键词
线粒体; 细胞凋亡; 氧化磷酸化; 粒线体; 能量代谢; 呼吸链电子传递;
D O I
暂无
中图分类号
R33 [人体生理学];
学科分类号
摘要
引用
收藏
页码:264 / 267
页数:4
相关论文
共 22 条
[1]  
Topology of superoxide production from different sites in the mitochondrial electron transport chain. St-Pierre J,Buckingham JA,Roebuck SJ,et al. Journal of Biological Chemistry . 2002
[2]  
Cytochrome c release from mitochondria in the aging heart: a possible mechanism for apoptosis with age. Phaneuf S,Leeuwenburgh C. American Journal of Physiology Regulatory . 2002
[3]  
Amyloid-bata: an antioxidant that becomes a pro-oxidant and critically contributes to Alzheimer′s disease. Kontush A. Free Radical Biology and Medicine . 2001
[4]  
Bcl-2, via its BH4 domain, blocks apoptotic signaling mediated by mitochondrial Ras. Denis GV,Yu Q,Ma P. Journal of Biological Chemistry . 2003
[5]  
Oxidative stress and mitochondrial DNA mutations in Humans ageing. Wei YH. Proceedings of the Society for Experimental Biology and Medicine . 1998
[6]  
Independent control of cell survival by Raf-1 and Bcl-2 at the mitochondria. J Zhong,J Troppmair. Oncegene . 2001
[7]  
Agedependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria. Chen D,Cao G,Hastings T,et al. Journal of Neurochemistry . 2002
[8]  
Fragmented mitochondrial DNA is the predominant carrier of oxidized DNA bases. Suter M,Richter C. Biochemistry . 1999
[9]  
Apoptosis and aging: role of mitochondria. Pollack M,Leeuwenburgh C. Journals of Gerontology Series A Biological Sciences and Medical Sciences The . 2001
[10]  
Mitochondrial DNA damage is more extensive and persists longer than DNA in human cells following oxidative stress. Yakas FM,Houtem BV. Proceedings of the National Academy of Sciences of the United States of America . 1997