CD36与动脉粥样硬化

被引：12

作者：

靳文英

陈红

机构：

[1] 北京大学人民医院心脏中心

来源：

中国动脉硬化杂志 | 2010年 / 07期

关键词：

CD36; 动脉粥样硬化; 清道夫受体;

D O I：

暂无

中图分类号：

R543 [血管疾病];

学科分类号：

1002 ; 100201 ;

摘要：

CD36是在多种组织细胞上表达的跨膜糖蛋白,属于B族清道夫受体。单核巨噬细胞上的CD36是吞噬摄取氧化型低密度脂蛋白的主要受体。除介导泡沫细胞形成外,CD36还有促进凝血和单核细胞聚集,促进炎症反应和氧化、凋亡等多种功能,其表达可被高度调控,是巨噬细胞泡沫化和动脉粥样硬化发生发展的重要因素。

引用

页码：582 / 585

页数：4

共 9 条

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