中晚期胃癌近十年治疗模式的转变

被引：10

作者：

周颖磊

黄镜

机构：

[1] 中国医学科学院北京协和医学院肿瘤医院内科

来源：

癌症进展 | 2014年 / 12卷 / 02期

关键词：

胃癌; 化疗; 靶向治疗;

D O I：

暂无

中图分类号：

R735.2 [胃肿瘤];

学科分类号：

100112 [医学生物化学与分子生物学];

摘要：

胃癌是我国常见的恶性肿瘤,我国每年新发病例数居全世界首位。近十年来,胃癌的治疗模式发生了显著的改变,局部晚期胃癌的治疗从单一的手术切除模式转化为化疗和手术相结合的综合治疗模式,晚期转移性胃癌从单纯化疗走向分子靶向药物治疗时代。目前针对Her-2或血管内皮生长因子受体(vascular endothelial growth factor receptor,VEGFR)基因为靶点的靶向治疗药物曲妥珠单抗、阿帕替尼(Apatinib)和Ramucirumab都在晚期胃癌的Ⅲ期随机对照临床研究中显示出明确的治疗效果。

引用

页码：104 / 107+139 +139

页数：5

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