PPARγ、UCP2与非乙醇性脂肪性肝病

被引：2

作者：

林海凤 ^{[1
]}

林志辉 ^{[2
]}

机构：

[1] 福建医科大学

[2] 福建省立医院消化内科

来源：

医学综述 | 2008年 / 04期

关键词：

非乙醇性脂肪性肝病; 过氧化物酶体增殖物激活受体γ; 解耦联蛋白2;

D O I：

暂无

中图分类号：

R575.5 [肝代谢障碍];

学科分类号：

100201 [内科学];

摘要：

研究显示过氧化物酶体增殖物激活受体γ和解耦联蛋白2参与了非乙醇性脂肪性肝病的发病。过氧化物酶体增殖物激活受体γ和胰岛素抵抗及脂肪细胞因子间有密切联系。解耦联蛋白2也可调节胰岛素分泌、限制活性氧产生、调节ATP合成等。阐明过氧化物酶体增殖物激活受体γ、解耦联蛋白2与非乙醇性脂肪性肝病之间的联系有助于进一步防治非乙醇性脂肪性肝病。

引用

页码：496 / 498

页数：3

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