糖尿病肾病足细胞损伤机制研究进展

被引：9

作者：

邬民香 ^{[1
]}

罗群 ^{[2
]}

机构：

[1] 宁波大学医学院

[2] 宁波市第二医院

来源：

现代实用医学 | 2012年 / 24卷 / 05期

关键词：

D O I：

暂无

中图分类号：

R692 [肾疾病];

学科分类号：

100221 [泌尿外科学];

摘要：

<正>糖尿病肾病(diabetic nephropathy,DN)是糖尿病的常见并发症,也是引起终末期肾病的的最常见病因之一。DN发生和进展受众多因素影响,近年来研究发现,肾素血管紧张素系统(renin-angiotensin system,RAS)的激活、活性氧自由基的增加、糖基化终产物、胰岛素敏感性的改变、脂联素缺乏及微小核糖核酸(RNA)等都会引起足细胞损伤,足细胞损伤后足突融合、足细胞与基底膜

引用

页码：598 / 600

页数：3

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