慢性心力衰竭住院患者贫血患病率的临床分析

被引:19
作者
林茂欢 [1 ]
林国垣 [1 ,2 ]
刘品明 [1 ]
黄至斌 [3 ]
王景峰 [1 ]
机构
[1] 中山大学附属孙逸仙纪念医院心内科
[2] 马泷日间医院
[3] 中山大学第一附属医院心内科
关键词
心力衰竭; 慢性; 贫血; 患病率; 危险因素;
D O I
暂无
中图分类号
R541.6 [血液循环衰竭];
学科分类号
100201 [内科学];
摘要
【目的】探讨慢性心衰(CHF)住院患者贫血患病率及其临床意义。【方法】回顾性分析中山大学孙逸仙纪念医院10年来符合入选条件的住院CHF患者相关资料,了解贫血(Hb<120 g/L)的患病率,比较贫血与非贫血患者的临床、生化特征及住院期间病死率,多因素Logistic分析贫血的危险因素。【结果】共纳入666例患者,平均年龄65(S=14)岁,平均Hb128(S=20)g/L。贫血患病率为32.58%。与非贫血患者相比,贫血的CHF患者多见于女性、年龄大、体质量低、合并高血压、基础病为冠心病,下肢水肿、肺水肿和胸腔积液更常见,eGFR、血浆白蛋白(ALB)低于非贫血组,而SCr、BUN、平均LVEF高于非贫血组,同时贫血组住院时间延长。贫血组住院期间病死率明显高于非贫血组(9.7%vs 5.3%,P=0.037)。多因素Logistic分析显示女性(OR=2.87,P<0.001)、年龄增加(每5岁,OR=1.09,P=0.02)、NYHA分级升高(OR=1.27,P=0.029)以及SCr升高(每10μmol/L,OR=1.08,P<0.001)是贫血的独立危险因素。【结论】CHF患者贫血的患病率较高,尤其在女性、高龄、心衰程度重以及肾功能下降患者,贫血增加CHF住院期间病死率。
引用
收藏
页码:668 / 672+692 +692
页数:6
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