阻塞性睡眠呼吸暂停低通气综合征患者的氧化应激状态和血管内皮的改变

被引：11

作者：

陈聆

李敏

机构：

[1] 上海交通大学医学院附属瑞金医院呼吸科

来源：

诊断学理论与实践 | 2009年 / 8卷 / 03期

关键词：

阻塞性睡眠呼吸暂停低通气综合征; 氧化应激; 血管内皮;

D O I：

10.16150/j.1671-2870.2009.03.013

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

<正>阻塞性睡眠呼吸暂停低通气综合征(obstructive sleepapnea hypopnea syndrome,OSAHS),是一种以夜间慢性间歇低氧(chronic intermittent hypoxia,CIH)为特征的睡眠呼吸紊乱,可导致包括心血管系统在内的多种靶器官损害。在

引用

页码：348 / 351

页数：4

共 8 条

[1]

Inflammation, Oxidative Stress, and Repair Capacity of the Vascular Endothelium in Obstructive Sleep Apnea[J] . Sanja Jelic,Margherita Padeletti,Steven M. Kawut,Christopher Higgins,Stephen M. Canfield,Duygu Onat,Paolo C. Colombo,Robert C. Basner,Phillip Factor,Thierry H. LeJemtel.Circulation . 2008 (17)

[2] Endothelial progenitor cells correlate with endothelial function in patients with coronary artery disease [J].

Werner, Nikos ;

Wassmann, Sven ;

Ahlers, Patrick ;

Schiegl, Tobias ;

Kosiol, Sonja ;

Link, Andreas ;

Walenta, Katrin ;

Nickenig, Georg .

BASIC RESEARCH IN CARDIOLOGY, 2007, 102 (06) :565-571

[3] Oxidative stress and oxidant signaling in obstructive sleep apnea and associated cardiovascular diseases [J].

Suzuki, Yuichiro J. ;

Jain, Vivek ;

Park, Ah-Mee ;

Day, Regina M. .

FREE RADICAL BIOLOGY AND MEDICINE, 2006, 40 (10) :1683-1692

[4] Oxidative stress in obstructive sleep apnea [J].

Yamauchi, M ;

Nakano, H ;

Maekawa, J ;

Okamoto, Y ;

Ohnishi, Y ;

Suzuki, T ;

Kimura, H .

CHEST, 2005, 127 (05) :1674-1679

[5] Endothelial progenitor cells are rapidly recruited to myocardium and mediate protective effect of ischemic preconditioning via "imported" nitric oxide synthase activity [J].

Ii, M ;

Nishimura, H ;

Iwakura, A ;

Wecker, A ;

Eaton, E ;

Asahara, T ;

Losordo, DW .

CIRCULATION, 2005, 111 (09) :1114-1120

[6] Oxygen administration improves the serum level of nitric oxide metabolites in patients with obstructive sleep apnea syndrome [J].

Teramoto, S ;

Kume, H ;

Matsuse, T ;

Ishii, T ;

Miyashita, A ;

Akishita, M ;

Toba, K ;

Ouchi, Y .

SLEEP MEDICINE, 2003, 4 (05) :403-407

[7]

Plasma levels of nitric oxide and L-arginine in sleep apnea patients[J] . Lena Lavie,Aya Hefetz,Rafael Luboshitzky,Peretz Lavie.Journal of Molecular Neuroscience . 2003 (1)

[8] Reactive oxygen metabolites (ROMs) as an index of oxidative stress in obstructive sleep apnea patients. [J].

Kostas Christou ;

Nikolaos Markoulis ;

Anargyros N. Moulas ;

Chaido Pastaka ;

Kostantinos I. Gourgoulianis .

Sleep and Breathing, 2003, 7 (3) :105-109

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