营养不良及低血锌儿童T细胞亚群的变化

被引:2
作者
曾柏锦
钱幼琼
郑德元
吴康敏
周呜生
龚其美
机构
[1] 华西医科大学儿科学教研室,华西医科大学儿科学教研室,华西医科大学儿科学教研室,华西医科大学儿科学教研室,华西医科大学微生物学与免疫学教研室,华西医科大学微生物学与免疫学教研室
关键词
营养不良; 低血锌; 儿童; T细胞亚群;
D O I
暂无
中图分类号
学科分类号
摘要
作者检测了60例6个月至3岁零8个月营养不良儿童的外周血T细胞亚群,结果表明:中、重度营养不良伴血锌降低;轻度营养不良患儿外周血全T细胞(OKT3+)、T辅助/诱导T细胞(OKT4+)、T抑制/细胞毒T细胞(0KT3+)低于正常。0KT3+、OKT4+细胞随营养不良程度的加重,其下降更明显。中、重度营养不良合并感染时,0KT3~+、0KT4+及OKT4+/OKT8+细胞比值明显低于无感染组,提示细胞免疫的主要效应及调节细胞受损。OKT3+、OKT4+细胞可作为早期检测营养不良患儿免疫功能有无受损的灵敏指标。
引用
收藏
页码:337 / 339
页数:3
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