中药漏芦抗动脉粥样硬化的实验研究

被引:9
作者
卢詠才 [1 ]
翁玉椿 [1 ]
刘小青 [1 ]
王秀萍 [1 ]
贾绪东 [1 ]
周玉琳 [1 ]
石方 [1 ]
汪健 [1 ]
甄二真 [1 ]
机构
[1] 北京中医学院中心实验室
关键词
漏芦; 动脉粥样硬化; 过氧化脂质; 膜流动性; 鹌鹑;
D O I
暂无
中图分类号
R28 [中药学];
学科分类号
1008 ;
摘要
用高脂饲料喂鹌鹑45天,70%发生动脉粥样硬化(AS)病变,同时测得红细胞膜Lpo含量比正常高,膜流动性比正常低。喂高脂饲料同时给漏芦水煎剂或维生素E,均使血胆固醇下降,红细胞膜Lpo含量减少和膜流动性升高,AS病变减轻、发生率降低,二药作用相似。认为抑制脂质过氧化、保护细胞膜结构的完整性可能是漏芦抗AS的作用机理之一。
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