超声直视下冠心病患者颈动脉斑块与hs-CRP、sICAM-1的相关性研究

被引：2

作者：

朱文晖

张梦玺

肖际东

张志辉

曹宇

欧阳茂

机构：

[1] 中南大学湘雅三医院超声科

[2] 中南大学湘雅三医院超声科湖南长沙

[3] 湖南长沙

来源：

医学临床研究 | 2005年 / 07期

基金：

湖南省自然科学基金;

关键词：

冠状动脉疾病/超声检查; 颈动脉; C反应蛋白质; 胞间粘附分子1;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

【目的】研究不同程度冠状动脉病变患者颈动脉内-中膜厚度(IMT)及斑块指数与血清高敏C反应蛋白(hsCRP),可溶性细胞间粘附分子1(sICAM1)的相关性。【方法】对82例入院接受冠状动脉造影的病人进行颈动脉超声检查,根据冠状动脉造影结果分为正常冠状动脉组,冠状动脉单支病变组,及冠状动脉多支病变组(双支或三支病变患者)。采用高频超声探测双侧颈动脉IMT和斑块指数,以及测定血清hsCRP,sICAM1含量。【结果】①冠状动脉多支病变组IMT,软斑指数,硬斑指数及总斑块指数明显高于正常组和IMT,软斑指数,总斑块指数明显高于冠状动脉单支病变组;冠状动脉多支病变组血清hsCRP,sICAM1含量亦明显高于正常组及冠状动脉单支病变组。②血清hsCRP和血清sICAM1与IMT,软斑指数,硬斑指数及总斑块指数均呈正相关。【结论】通过颈动脉超声检测,可以初步预测冠状动脉病变程度与颈动脉粥样斑块及炎性因子的关系。

引用

页码：865 / 867+870 +870

页数：4

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