糖尿病心肌病发病机制的研究进展

被引：30

作者：

潘大彬 ^{[1
]}

汪旻晖 ^{[2
]}

曹蘅 ^{[1
]}

机构：

[1] 皖南医学院心血管疾病研究所暨弋矶山医院心内科

[2] 皖南医学院弋矶山医院临床药学部

来源：

中国临床药理学与治疗学 | 2013年 / 18卷 / 07期

关键词：

糖尿病; 心肌病; 发病机制; 心肌病/糖尿病性; 高血糖;

D O I：

暂无

中图分类号：

R542.2 [心肌疾病]; R587.2 [糖尿病性昏迷及其他并发症];

学科分类号：

100201 [内科学];

摘要：

糖尿病威胁人类的健康日益突出。高血糖引起的心血管并发症涉及到心肌病变和血管病变。而糖尿病引起的糖尿病心肌病发病机制是由多因素所致,糖尿病通过各种心肌细胞器结构的改变(线粒体、内质网等)、信号途径、酶学及基因学的变化和炎症因子等病理机制,导致心脏纤维化、心肌肥厚、心脏扩大、心力衰竭和心律失常。本综述详细阐述糖尿病心肌病发病机制的研究进展。

引用

页码：831 / 836

页数：6

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