杜仲有效成分在帕金森病治疗中的药理作用研究进展

被引：11

作者：

柴士伟 ^{[1
]}

马静 ^{[2
]}

庄朋伟 ^{[2
]}

张艳军 ^{[2
]}

郭虹 ^{[2
]}

机构：

[1] 天津中医药大学第一附属医院

[2] 天津中医药大学天津市现代中药重点实验室-省部共建国家重点实验室培育基地

来源：

药物评价研究 | 2019年 / 42卷 / 05期

关键词：

杜仲; 帕金森病; 有效成分;

D O I：

暂无

中图分类号：

R285.5 [中药实验药理];

学科分类号：

摘要：

帕金森病(Parkinson’s Disease, PD)是中老年人常见的神经系统变性疾病,其发病可受年龄、遗传和环境等因素影响,其主要病理机制为大脑黑质致密部多巴胺能神经元的病变缺失。保护多巴胺能神经元是行之有效的方法之一,脑内炎症反应、氧化应激等均可导致神经细胞的损伤。杜仲是常用补益中药,具有明确的神经保护作用,临床常用于PD的治疗,对近年杜仲及其有效成分在PD治疗中的药理作用研究进展做一综述,以期为杜仲在防治PD方面的开发应用提供一定线索。

引用

页码：1003 / 1009

页数：7

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