造血干细胞的可塑性及临床应用

被引：6

作者：

陈运贤

钟雪云

欧瑞明

机构：

[1] 中山大学附属第一医院血液内科,暨南大学医学院病理学教研室,中山大学附属第一医院血液内科广东广州,广东广州,广东广州

来源：

中国病理生理杂志 | 2002年 / 12期

关键词：

干细胞; 可塑性; 横向分化;

D O I：

暂无

中图分类号：

R457 [血液疗法];

学科分类号：

摘要：

Traditional concept has been that hematopoietic stem cells (HSC) are tissue-specific stem cells, which are restricted to generate the cell types of the blood and immune system. However, recent studies have shown that there is a higher plasticity of the HSC than previous expected, it can be induced to transdifferentiated into mature cells of other nonhematopoietic organs after transplantation in vivo. In this article, the recent advances in the plasticity of HSC and its potential clinical application are reviewed.

引用

页码：93 / 96

页数：4

共 22 条

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韩忠朝
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陈惠珍
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