高迁移率族蛋白1在中枢神经系统疾病中的作用

被引：3

作者：

周瑞

曹红

李军

机构：

[1] 温州医学院附属第二医院麻醉科

来源：

国际麻醉学与复苏杂志 | 2009年 / 02期

基金：

浙江省自然科学基金;

关键词：

高迁移率族蛋白1; 中枢神经系统疾病; 脑缺血;

D O I：

暂无

中图分类号：

R741 [神经病学];

学科分类号：

1002 ;

摘要：

高迁移率族(high mobiliby group box,HMGB)蛋白是一类核蛋白,释放至细胞外的HMGB1参与了外周诸多疾病的发生。近年来研究表明,HMGB1也参与了中枢神经系统疾病的发生。现简要阐述HMGB1的外周作用,着重介绍其在中枢神经系统疾病,特别脑缺血中的作用。

引用

页码：143 / 147

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