代谢综合征与脑卒中的循证医学证据

被引:6
作者
李伟 [1 ]
刘鸣 [2 ]
宋允章 [1 ]
杨谦 [1 ]
机构
[1] 陕西省人民医院神经内科
[2] 四川大学华西医院神经内科
关键词
代谢疾病; 卒中; 循证医学; 综述文献;
D O I
暂无
中图分类号
R589 [代谢病]; R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ; 100201 ;
摘要
<正> 代谢综合征(MS)亦称为胰岛素抵抗综合征(IRS),是心血管疾病的多种代谢危险因素在体内并存的状态。1988年,Reaven首先系统描述了代谢综合征的特点,此后大量关于其病理生理学、流行病学,以及治疗策略和预后的研究见诸文献。Reaven定义的代谢综合征包括腹部肥胖、高血糖、高甘油三酯血症、低高密度脂蛋白血症和高血压。上述危险因素的综合作用增加了心脑血管疾病的风险。胰岛素抵抗是代谢综合征的病理生理学基础。1998年,世界卫生组织(WHO)和美国分别制订了代谢综合征诊断标准,尽管二者存在小的差异,但总体内容获得共识,已有多项临床研究以这两项标准作为诊断依据。近20年来,中国经济飞速发展导致同人饮食结构和生活方式明显改变,肥胖、脂质代谢紊乱、高血压和糖尿病的发病率显著
引用
收藏
页码:428 / 429
页数:2
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