CRP与动脉粥样硬化斑块稳定性的研究进展

被引：9

作者：

赵红敏

王铭维

王彦永

机构：

[1] 河北医科大学第一医院

来源：

临床合理用药杂志 | 2012年 / 5卷 / 20期

关键词：

C反应蛋白; 炎性反应; 动脉粥样硬化斑块,稳定期; 研究进展;

D O I：

10.15887/j.cnki.13-1389/r.2012.20.062

中图分类号：

R543.5 [动脉疾病];

学科分类号：

摘要：

<正>脑梗死是目前发病率高、残疾率高、病死率高的一种疾病,动脉粥样硬化是常见的致病因子之一。目前研究证实,炎性反应在动脉粥样硬化的发生发展中起着重要作用[1]。C反应蛋白(CRP)作为炎性反应的敏感因子,已被证实是反映动脉粥样硬化的敏感指标,CRP浓度的增加伴随着心脑血管事件风险的增加,是一个极有价值的预报因子[2、3]。

引用

页码：165 / 166

页数：2

共 24 条

[1] 冠心病患者血清C反应蛋白检测的临床意义 [J].

涂燕平 ;

龚爱斌 ;

魏伟荣 ;

王凌玲 .

临床心血管病杂志, 2002, (02) :89-89

[2]

Atherosclerosis-an inflammatory disease. Ross R. New England Journal of Homeopathy . 1999

[3]

Prediction of Clinical Cardiovascular Events With Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis[J] . Matthias W. Lorenz,Hugh S. Markus,Michiel L. Bots,Maria Rosvall,Matthias Sitzer. &nbspCirculation . 2007 (4)

[4]

Interferon-gamma and lipopolysaccharide potentiate monocyte tissue factor induction by C-reactive protein: relationship with age, sex, and hormone replacement treatment. Nakagomi A, Freedman SB, Geczy CL. Circulation . 2000

[5] 动脉粥样硬化——一种慢性炎症过程 [J].

徐也鲁 .

中国动脉硬化杂志, 2001, (02) :93-95

[6]

Expression of the adhesion molecules ICAM VCAM and ELAM in the arte-riosclerotic plaque. Kasper H U,Schmidt A,Roessner A. General and Diagnostic Pathology . 1996

[7]

Abdominal adiposity is associated with elevated C-reactive protein independent of BMI in healthy nonobese people. E Lapice,S Maione,L Patti,P Cipriano,AA Rivellese,G Riccardi. Diabetes Care . 2009

[8]

Clinical feasibility of molec-ular imaging of plaque inflammation in atherosclerosis. Tahara N,Imaizumi T,Vinnani R,et al. The Journal of Nuclear Medicine . 2009

[9]

Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells. Calabro P, Willerson JT, Yeh ET. Circulation . 2003

[10]

Low-Grade Inflammation Is a Risk Factor for Clinical Stroke Events in Addition to Silent Cerebral Infarcts in Japanese Older Hypertensives: The Jichi Medical School ABPM Study, Wave 1[J] . Joji Ishikawa,Yurie Tamura,Satoshi Hoshide,Kazuo Eguchi,Shizukiyo Ishikawa,Kazuyuki Shimada,Kazuomi Kario. &nbspStroke . 2007 (3)

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