共 2 条
[1]
[2]
离体鼠肝细胞膜上甘草次酸和甘草酸受体的表达.[J].杨山麦;周方成;顾云娣;刘水腾;蒋小玲;成令忠.中华肝脏病杂志.1999, S1
肝靶向甘草次酸修饰的壳聚糖纳米粒子的合成和表征
被引：16
作者：
查瑞涛
贺晓婷
杜田
袁直
机构：
[1] 南开大学高分子化学研究所功能高分子材料教育部重点实验室
来源：
基金：
天津市自然科学基金;
关键词：
甘草次酸;
壳聚糖;
肝靶向;
D O I：
暂无
中图分类号：
TQ460.6 [制药工艺];
学科分类号：
100705 [微生物与生化药学];
摘要：
Chitosan derivative with glycyrrhetinic acid(GA),which was accumulated specifically in liver,was synthesized.By ion-crosslinking of TPP in GA-CTS solution,GA-CTS-TPP complex nanoparticles were obtained.The physicochemical properties of these nanoparticles were investigated by using TEM and DLS.The experiment in vitro BSA entrapped was studied.GA-CTS-TPP nanoparticles are well dispersed and stable in aqueous solution in 14 months.
引用
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页码：1098 / 1100
页数：3
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