糖皮质激素与COPD合并肺癌

被引:5
作者
金珊珊
陈小岚
王兴友
机构
[1] 北京军区总医院呼吸内科
关键词
慢性阻塞性肺疾病; 肺癌; 糖皮质激素;
D O I
暂无
中图分类号
R563.9 [其他]; R734.2 [肺肿瘤];
学科分类号
100117 [系统生物医学]; 100201 [内科学];
摘要
大气污染及吸烟是COPD的主要致病因素, 目前发病率呈逐渐增高趋势, 且居全球死亡原因的第4位, 合并肺癌的也较常见。COPD合并肺癌患者存在不同的肺功能损伤, 导致肺功能异常, 细胞因子及炎症因子异常分泌及浓聚, 因此糖皮质激素近年来被推荐用于COPD稳定期和急性加重期的治疗, 同时也被发现在肺癌的预防治疗中可减轻放、化疗不良反应。为了探讨肺癌和COPD的相关性, 我们就近年来肺癌和COPD在炎症反应方面所取得的进展进行回顾和综述, 探讨糖皮质激素在肺癌治疗中的重要意义, 以期在肺癌的临床诊疗工作中起到积极影响。
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