脑缺血性疾病治疗进展

被引：6

作者：

王学颖

余丹

机构：

[1] 中南大学湘雅医学院附属海口医院神经内科

来源：

中华临床医师杂志(电子版) | 2013年 / 7卷 / 15期

关键词：

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

100204 [神经病学];

摘要：

<正>脑缺血性疾病是神经系统的多发病、常见病,其发病率死亡率致残率之高,严重影响患者的生活质量,并给家庭和社会带来了沉重的经济及精神负担。脑缺血性疾病指脑组织血供障碍引起的相应区域的缺血、缺氧,引发脑组织的一系列的病理生理生化等变化,最终造成脑组织的损害及相应组织区域功能的缺失。脑缺血疾病发生的根本机制及最终结局均为脑组织的缺血、缺氧及再灌注损伤。因此,目前脑缺血性疾病的治疗目标也在于恢复血供、氧供,阻断脑缺血后的一系列级联反应,从而维持脑结构及功能的完整性。随着研究的深入,目前已经研发出许多可以改善神经功能及限制脑缺血后病理变化的治疗措施。一、脑缺血后血管再通治疗脑缺血后脑组织的缺血缺氧的发生是由于相应供血血管的血流的中断所致,受累血管管腔的再通是脑缺血迅速而有效的

引用

页码：7112 / 7114

页数：3

共 23 条

[1]

Long Course Hyperbaric Oxygen Stimulates Neurogenesis and Attenuates Inflammation after Ischemic Stroke.[J].Ying-Sheng Lee;Chung-Ching Chio;Ching-Ping Chang;Liang-Chao Wang;Po-Min Chiang;Kuo-Chi Niu;Kuen-Jer Tsai;I-Ming Jou.Mediators of Inflammation.2013,

[2]

Self-Expandable Stents in the Treatment of Acute Ischemic Stroke Refractory to Current Thrombectomy Devices [J].

Linfante, Italo ;

Samaniego, Edgar A. ;

Geisbuesch, Philipp ;

Dabus, Guilherme .

STROKE, 2011, 42 (09) :2636-2638

[3]

Mechanical Thrombectomy for Acute Ischemic Stroke Using the MERCI Retriever and Penumbra Aspiration Systems [J].

Tenser, Matthew S. ;

Amar, Arun P. ;

Mack, William J. .

WORLD NEUROSURGERY, 2011, 76 (06) :S16-S23

[4]

Ultrasound-Assisted Thrombolysis for Stroke Therapy: Better Thrombus Break-Up With Bubbles.[J].Kathryn E. Hitchcock;Christy K. Holland.Stroke.2010, 10 S

[5]

Wingspan in-stent restenosis and thrombosis: Incidence, clinical presentation, and management [J].

Levy, Elad I. ;

Turk, Aquilla S. ;

Albuquerque, Felipe C. ;

Niemann, David B. ;

Aagaard-Kienitz, Beverly ;

Pride, Lee ;

Purdy, Phil ;

Welch, Babu ;

Woo, Henry ;

Rasmussen, Peter A. ;

Hopkins, L. Nelson ;

Masaryk, Thomas. ;

McDougall, Cameron G. ;

Fiorella, David J. .

NEUROSURGERY, 2007, 61 (03) :644-650

[6]

Efficacy and safety of anticoagulant treatment in acute cardioembolic stroke - A meta-analysis of randomized controlled trials [J].

Paciaroni, Maurizio ;

Agnelli, Giancarlo ;

Micheli, Sara ;

Caso, Valeria .

STROKE, 2007, 38 (02) :423-430

[7]

Stent-assisted intracranial recanalization for acute stroke: Early results [J].

Levy, EI ;

Ecker, RD ;

Horowitz, MB ;

Gupta, R ;

Hanel, RA ;

Sauvageau, E ;

Jovin, TG ;

Guterman, LR ;

Hopkins, LN .

NEUROSURGERY, 2006, 58 (03) :458-462

[8]

Emergent stenting of extracranial internal carotid artery occlusion in acute stroke has a high revascularization rate [J].

Jovin, TG ;

Gupta, R ;

Uchino, K ;

Jungreis, CA ;

Wechsler, LR ;

Hammer, MD ;

Tayal, A ;

Horowitz, MB .

STROKE, 2005, 36 (11) :2426-2430

[9]

Local Saline Infusion into Ischemic Territory Induces Regional Brain Cooling and Neuroprotection in Rats with Transient Middle Cerebral Artery Occlusion.[J].Yuchuan Ding;Jie Li;Xiaodong Luan;Qin Lai;James P. McAllister;John W. Phillis;Justin C. Clark;Murali Guthikonda;Fernando G. Diaz.Neurosurgery.2004, 4

[10]

Mild hypothermia reduces expression of heat shock protein 60 in leukocytes from severely head-injured patients [J].

Hashiguchi, N ;

Shiozaki, T ;

Ogura, H ;

Tanaka, H ;

Koh, T ;

Noborio, M ;

Fugita, K ;

Akimau, P ;

Kuwagata, Y ;

Shimazu, T ;

Sugimoto, H .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2003, 55 (06) :1054-1060

← 1 2 3 →