心肌缺血后处理胞内信号转导研究进展

被引：13

作者：

徐宪连

张英杰

机构：

[1] 辽宁医学院附属第一医院

来源：

生命科学 | 2008年 / 01期

关键词：

缺血后处理; 再灌注损伤补救激酶; 信号转导;

D O I：

暂无

中图分类号：

R541 [心脏疾病];

学科分类号：

摘要：

缺血后处理对心肌再灌注损伤的保护是多因素参与的复杂过程。后处理对心肌的保护除了通过减少活性氧类物质的产生、抑制线粒体内钙超载、减轻内皮功能失调等被动作用外,还可主动激活再灌注损伤补救激酶(reperfusion injury salvage kinase,RISK)途径及其他蛋白激酶而实现。本文将对心肌缺血后处理中RISK通路的研究进展作一综述。

引用

页码：116 / 119

页数：4

共 11 条

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