Helicobacter pylori therapy:Present and future

被引:9
作者
Vincenzo De Francesco [1 ]
Enzo Ierardi [1 ]
Cesare Hassan [2 ]
Angelo Zullo [2 ]
机构
[1] Gastroenterology Unit,Department of Medical Sciences,University of Foggia,Ospedali Riuniti,71100 Foggia,Italy
[2] Gastroenterology and Digestive Endoscopy,"Nuovo Regina Margherita" Hospital,00153 Rome,Italy
关键词
Helicobacter pylori; Antibiotic resistance; Virulence factors; Therapy; Eradication;
D O I
暂无
中图分类号
R573 [胃疾病];
学科分类号
1002 ; 100201 ;
摘要
Helicobacter pylori(H.pylori) plays a crucial role in the pathogenesis of chronic active gastritis,peptic ulcer and gastric mucosa-associated lymphoid tissue-lymphoma,and is also involved in carcinogenesis of the stomach.H.pylori treatment still remains a challenge for physicians,since no current first-line therapy is able to cure the infection in all treated patients.Several factors may help in the eradication of therapy failure.We reviewed both bacterial and host factors involved in therapeutic management of the H.pylori infection.In addition,we evaluated data on the most successful therapy regimens-sequential and concomitant therapies-currently available for H.pylori eradication.
引用
收藏
页码:68 / 73
页数:6
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