2型糖尿病合并非酒精性脂肪肝发病机制的研究进展

被引：17

作者：

刘阳 ^{[1
]}

陈冉 ^{[2
]}

于世家 ^{[1
]}

文涛 ^{[3
]}

机构：

[1] 辽宁中医药大学附属医院内分泌科

[2] 辽宁中医药大学

[3] 辽宁省疾病预防控制中心卫生毒理所

来源：

基础医学与临床 | 2018年 / 38卷 / 08期

关键词：

2型糖尿病; 非酒精性脂肪肝; 分子机制;

D O I：

10.16352/j.issn.1001-6325.2018.08.022

中图分类号：

R575.5 [肝代谢障碍]; R587.2 [糖尿病性昏迷及其他并发症];

学科分类号：

100201 [内科学];

摘要：

随着饮食结构和生活方式的改变,2型糖尿病合并非酒精性脂肪肝的患者不断增多,其发病机制相关分子包括FGF21、Fetuin-A、SREBP-1、PPARα、IGFBP-1、IGF-1、TNF-α、CTRP3和AMPK等。期待不久的将来可以针对其分子靶点研发出高效的治疗非酒精性脂肪肝的药物。

引用

页码：1163 / 1167

页数：5

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