SDF-1/CXCR4在女性生殖系统肿瘤及胚胎着床中的作用

被引：4

作者：

徐楗荧

朱伟杰

机构：

[1] 暨南大学生命科技学院

[2] 生殖免疫研究所

[3] 广州

来源：

中华生殖与避孕杂志 | 2010年 / 01期

关键词：

基质细胞衍生因子-1; CXCR4; 肿瘤; 胚胎;

D O I：

暂无

中图分类号：

R737.3 [女性生殖器肿瘤];

学科分类号：

100214 ;

摘要：

基质细胞衍生因子-1(stromal cell-derived factor 1, SDF-1)是CXC趋化因子家族的成员, CXCR4是目前已知SDF-1的唯一受体。SDF-1/CXCR4在调控胚胎着床, 诱导胎盘血管生成, 肿瘤细胞趋向性侵袭、转移等方面发挥作用。本文综述SDF-1/CXCR4在女性生殖系统肿瘤中的研究现状, 及其在胚胎着床过程中的作用。

引用

页码：46 / 49

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