导管直接溶栓治疗下肢深静脉血栓形成

被引：72

作者：

黄晓钟

梁卫

叶猛

张纪蔚

机构：

[1] 上海交通大学医学院附属仁济医院血管外科

来源：

介入放射学杂志 | 2008年 / 01期

关键词：

深静脉血栓形成; 导管直接溶栓; 尿激酶;

D O I：

暂无

中图分类号：

R543 [血管疾病];

学科分类号：

1002 ; 100201 ;

摘要：

目的通过观察导管直接溶栓治疗急性下肢深静脉血栓形成(DVT)的临床效果以及随访结果,评价该方法治疗急性下肢DVT的疗效。方法104例急性下肢DVT患者,于DSA下,溶栓导管直接插入静脉血栓,微泵持续推注尿激酶(154.27±76.31)万u溶栓。14例溶栓后行腔内成形支架放置治疗。以静脉通畅评分和静脉通畅率及健患肢周径差指标评价疗效,治疗半年以上随访。结果92例治疗后静脉造影复查显示,静脉通畅评分显著改善(P<0.01),静脉通畅率52.4%±16.4%。治疗过程中未出现严重并发症。53例随访6～26(13.5±7.3)个月(随访率51.0%)。静脉造影显示,静脉通畅评分显著改善(P<0.01),静脉通畅率为63.7%±17.3%。46例深静脉瓣膜得以保存,深静脉瓣膜保存率达83.7%。结论导管直接溶栓治疗急性下肢DVT,是一种疗效良好而且安全的治疗方法。

引用

页码：11 / 14

页数：4

共 13 条

[1] 介入腔内溶栓治疗急性下肢深静脉血栓形成 [J].

黄晓钟 ;

张纪蔚 ;

梁卫 ;

池家昌 .

介入放射学杂志, 2006, (10) :592-596

[2] 经腘静脉穿刺介入治疗髂股静脉阻塞 [J].

顾建平 ;

何旭 ;

楼文胜 ;

陈亮 ;

苏浩波 ;

陈国平 .

中华放射学杂志, 2005, (09) :26-29

[3] Percutaneous treatment of deep vein thrombosis in May-Thurner syndrome [J].

Kim, Jong-Youn ;

Choi, Donghoon ;

Ko, Young Guk ;

Park, Sungha ;

Jang, Yangsoo ;

Lee, Do Yun .

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2006, 29 (04) :571-575

[4]

Catheter Directed Thrombolysis for Treatment of Ilio-femoral Deep Venous Thrombosis is Durable, Preserves Venous Valve Function and May Prevent Chronic Venous Insufficiency[J] . European Journal of Vascular & Endovascular Surgery . 2005 (5)

[5]

Stents in Common Iliac Vein Obstruction with Acute Ipsilateral Deep Venous Thrombosis: Early and Late Results[J] . Hyo-Sung Kwak,Young-Min Han,Young-Sun Lee,Gong-Yong Jin,Gyung-Ho Chung.Journal of Vascular and Interventional Radiology . 2005 (6)

[6] Preservation of venous valve function after catheter- directed and systemic thrombolysis for deep venous thrombosis [J].

Laiho, MK ;

Oinonen, A ;

Sugano, N ;

Harjola, VP ;

Lehtola, AL ;

Roth, WD ;

Keto, PE ;

Lepäntalo, M .

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2004, 28 (04) :391-396

[7]

Comparison of Urokinase, Alteplase, and Reteplase for Catheter-directed Thrombolysis of Deep Venous Thrombosis[J] . Michael R. Grunwald,Lawrence V. Hofmann.Journal of Vascular and Interventional Radiology . 2004 (4)

[8]

Thrombolysis of Acute Peripheral Arterial and Venous Occlusions with Tenecteplase and Eptifibatide: A Pilot Study[J] . David J. Burkart,John J. Borsa,James P. Anthony,Stephanie R. Thurlo.Journal of Vascular and Interventional Radiology . 2003 (6)

[9]

The safety, efficacy, and pharmacoeconomics of low-dose alteplase compared with urokinase for catheter-directed thrombolysis of arterial and venous occlusions[J] . Koji Sugimoto,Lawrence V. Hofmann,Mahmood K. Razavi,Stephen T. Kee,Daniel Y. Sze,Michael D. Dake,Charles P. Semba.Journal of Vascular Surgery . 2003 (3)

[10]

Early Results of Thrombolysis vs Anticoagulation in Iliofemoral Venous Thrombosis. A Randomised Clinical Trial[J] . M. Elsharawy,E. Elzayat.European Journal of Vascular & Endovascular Surgery . 2002 (3)

← 1 2 →