应激反应的细胞损伤和抗损伤机制及其调控

被引:22
作者
冯刚
机构
[1] 第三军医大学野战外科研究所四室!重庆
关键词
应激反应; 应激蛋白; 应激活化蛋白激酶;
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
组织细胞在受到包括创伤在内的各种外界刺激作用下发生应激反应。应激反应对细胞的作用包括损伤保护和损伤两方面,其中损伤保护作用主要由应激蛋白承担,而损伤效应则由应激活化蛋白激酶介导。这两个系统虽然各自介导对立的细胞反应,但又互相影响。本文综述了近年来应激蛋白和应激活化蛋白激酶的分子生物学特性及其各自在细胞应激反应中的作用研究,以及它们之间可能的相互调节机制。
引用
收藏
页码:51 / 53
页数:3
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