脂联素在肥胖相关疾病中的作用

被引：10

作者：

应志强

徐耕

机构：

[1] 浙江大学医学院附属第二医院心内科

来源：

国际内科学杂志 | 2008年 / 01期

关键词：

脂联素; 肥胖相关疾病; 胰岛素抵抗;

D O I：

暂无

中图分类号：

R589.2 [脂肪代谢障碍];

学科分类号：

1002 ; 100201 ;

摘要：

脂联素(APN)是白色脂肪等组织分泌的一种循环激素,在调节糖、脂代谢和抗炎中起重要作用。肥胖患者的血浆脂联素水平明显降低,低脂联素血症已被确认是2型糖尿病、冠心病和高血压等肥胖相关疾病的独立危险因素。本文就脂联素的结构、功能及其在胰岛素抵抗等代谢性疾病、冠状动脉硬化和高血压性心脏病中的保护作用作一综述。

引用

页码：11 / 14

页数：4

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