急性脑梗死合并心脏病对患者短期预后的影响

被引:15
作者
高连波
于长江
高红华
李明
机构
[1] 中国医科大学附属第四医院神经内科
关键词
脑梗死; 心脏病; 心电描记术; 预后;
D O I
暂无
中图分类号
R743.33 [脑栓塞];
学科分类号
摘要
目的探讨急性脑梗死合并心脏病对患者短期预后的影响。方法选取2010年12月—2012年12月我院神经内科收治的急性脑梗死患者233例,在发病48 h内(入组时)、发病第7天及第(14±2)天分别监测患者的心电图。根据牛津郡社区卒中项目(TOAST)分型进行卒中分型;根据改良Rankin量表(mRS)评分将预后分为预后良好和预后不良;根据美国国立卫生研究院卒中量表(NIHSS)评分差值将预后分为预后极差、预后不良、预后一般和预后良好。结果 (1)233例患者研究期间共149例(63.95%)发生心电图异常;入组时、发病第7天、发病第(14±2)天心电图异常率〔52.79%(123/233)、55.79%(130/233)、51.07%(119/233)〕间无差异(P>0.05),其中ST-T改变者比例分别为69.11%(85/123)、67.69%(88/130)和77.31%(92/119)。(2)心电图异常者的责任血管、卒中分型与心电图正常组比较无差异(P>0.05),但两组的病灶位置间有差异(P<0.05)。(3)根据mRS评分,ST-T改变者发病第7天、发病第(14±2)天的预后优于心律异常者(P<0.05);根据NIHSS评分差值,心电图正常者的预后优于心电图异常者(P<0.05)。(4)多因素非条件Logistic回归分析显示,心房纤颤是急性脑梗死伴发心功能异常者预后不良的危险因素〔OR=3.070,95%CI(1.118,8.430),P=0.029〕。结论急性脑梗死患者容易诱发心功能异常,早期出现心电图改变,主要为ST-T改变,其与短期预后密切相关。脑叶梗死更易诱发急性脑梗死患者短期内的心电图异常。急性脑梗死合并心脏病者常预后不良,尤其是合并心房纤颤者。
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页码:980 / 983+988 +988
页数:5
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