丹参酮ⅡA药理作用的研究进展

被引：64

作者：

李筱筱 ^{[1
]}

武雪玲 ^{[1
]}

贾世亮 ^{[1
]}

戴雪伶 ^{[1
,2
]}

孙雅煊 ^{[1
]}

机构：

[1] 北京联合大学应用文理学院

[2] 北京联合大学生物活性物质与功能食品北京市重点实验室

来源：

生物学杂志 | 2016年 / 33卷 / 06期

关键词：

丹参; 丹参酮ⅡA; 药理作用; 研究前景;

D O I：

暂无

中图分类号：

R285.5 [中药实验药理];

学科分类号：

100806 [中药药理学];

摘要：

丹参酮ⅡA(TanshinoneⅡA)是从中药丹参中分离提取得到的一种脂溶性的二萜醌类成分。药理研究表明丹参酮ⅡA在心血管疾病的治疗方面以及在神经保护和缺血再灌注损伤的保护方面发挥着明显的作用,其抗炎、抗氧化、抗肿瘤等多种生物学活性作用也扩大了丹参酮ⅡA应用范围。主要就丹参酮ⅡA药理作用及机制研究现状作综述,为丹参及丹参酮ⅡA的深入开发利用提供参考,以期丹参及丹参酮ⅡA可以发挥最大的药用价值。

引用

页码：91 / 94

页数：4

共 33 条

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[2]

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[3]

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PHYTOMEDICINE, 2015, 22 (10) :929-938

[4]

Tanshinone IIA attenuates renal fibrosis and inflammation via altering expression of TGF-β/Smad and NF-κB signaling pathway in 5/6 nephrectomized rats [J].

Wang, Dong-Tao ;

Huang, Ren-Hua ;

Cheng, Xin ;

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INTERNATIONAL IMMUNOPHARMACOLOGY, 2015, 26 (01) :4-12

[5]

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[6]

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[7]

Sodium tanshinone IIA sulfonate prolongs the survival of skin allografts by inhibiting inflammatory cell infiltration and T cell proliferation [J].

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INTERNATIONAL IMMUNOPHARMACOLOGY, 2014, 22 (01) :277-284

[8]

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[9]

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Xu, Xiao .

LIFE SCIENCES, 2014, 112 (1-2) :59-67

[10]

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