肝纤维化进程中细胞外基质对肝星状细胞的作用及机制研究进展

被引：37

作者：

秦雨萌

陈胜华

机构：

[1] 南华大学医学院解剖学教研室

来源：

实用肝脏病杂志 | 2017年 / 20卷 / 03期

关键词：

肝纤维化; 细胞外基质; 肝星状细胞;

D O I：

暂无

中图分类号：

R575.2 [肝硬变];

学科分类号：

100201 [内科学];

摘要：

肝纤维化是一种肝内弥漫性细胞外基质(ECM)过度沉积的病理过程,且肝星状细胞(HSC)的激活是肝纤维化发生发展的中心环节。本文主要介绍了在肝纤维化进程中ECM各种成分比例、分子结构的改变及其ECM分子空间结构改变对HSC的激活、增殖和凋亡的作用和机制。

引用

页码：381 / 384

页数：4

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