丹参、川芎嗪及糖皮质激素对肺纤维化保护作用的实验观察

被引:21
作者
陈祥银 [1 ]
严仪昭 [1 ]
曾卫东 [1 ]
李艳 [1 ]
李长城 [1 ]
机构
[1] 中国医学科学院基础医学研究所病理生理室
关键词
D O I
暂无
中图分类号
R285.5 [中药实验药理];
学科分类号
1008 ;
摘要
以平阳霉素气管内一次给药复制小白鼠肺纤维化模塑。观察了丹参注射液、川芎嗪注射液及氢化考的松琥珀酸钠对该模型发生的影响。结果表明,在本实验条件下,丹参及川芎嗪对肺纤维化发生的抑制作用似优于氢化考的松。讨论了其作用的可能机理。
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