血清可溶性CD36水平与2型糖尿病并非酒精性脂肪肝关系的研究进展

被引:5
作者
王福慧 [1 ]
曹岚 [1 ]
李博 [2 ]
金凤表 [1 ]
侯瑞田 [2 ]
机构
[1] 承德医学院附属医院内分泌科
[2] 承德医学院附属医院心内科
关键词
2型糖尿病; 非酒精性脂肪性肝病; 可溶性CD36; 动脉粥样硬化;
D O I
暂无
中图分类号
R575.5 [肝代谢障碍]; R587.1 [糖尿病];
学科分类号
100201 [内科学];
摘要
近年来2型糖尿病(type 2 diabetes mellitus,T2DM)并非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)发病率逐年增加。血清可溶性CD36(soluble CD36,sCD36)与胰岛素抵抗、炎症反应、糖脂代谢、动脉粥样硬化的发生密切相关,在T2DM并NAFLD的发生、发展中发挥重要作用,但有关sCD36与T2DM并NAFLD关系的研究较少。本文就血清sCD36水平与T2DM、NAFLD、T2DM并NAFLD关系的研究进展作一综述。
引用
收藏
页码:726 / 728
页数:3
相关论文
共 13 条
[1]
NAFLD: A multisystem disease.[J].Christopher D. Byrne;Giovanni Targher.Journal of Hepatology.2015, 1
[2]
Free Fatty Acid Uptake in Humans With CD36 Deficiency [J].
Hames, Kazanna C. ;
Vella, Adrian ;
Kemp, Bradley J. ;
Jensen, Michael D. .
DIABETES, 2014, 63 (11) :3606-3614
[3]
Increased soluble CD36 is linked to advanced steatosis in nonalcoholic fatty liver disease [J].
Garcia-Monzon, Carmelo ;
Lo Iacono, Oreste ;
Crespo, Javier ;
Romero-Gomez, Manuel ;
Garcia-Samaniego, Javier ;
Fernandez-Bermejo, Miguel ;
Dominguez-Diez, Agustin ;
Rodriguez de Cia, Javier ;
Saez, Alicia ;
Luis Porrero, Jose ;
Vargas-Castrillon, Javier ;
Chavez-Jimenez, Enrique ;
Soto-Fernandez, Susana ;
Diaz, Ainhoa ;
Gallego-Duran, Rocio ;
Madejon, Antonio ;
Eugenia Miquilena-Colina, Maria .
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2014, 44 (01) :65-73
[4]
Nonalcoholic fatty liver disease: an emerging threat to obese and diabetic individuals.[J].Howard C. Masuoka;Naga Chalasani.Annals of the New York Academy of Sciences.2013, 1
[5]
An Emerging Role of Glucagon-Like Peptide-1 in Preventing Advanced-Glycation-End-Product-Mediated Damages in Diabetes.[J].Alessandra Puddu;Fran?ois Mach;Alessio Nencioni;Giorgio Luciano Viviani;Fabrizio Montecucco;Dennis D. Taub.Mediators of Inflammation.2013,
[6]
CD36 as a target to prevent cardiac lipotoxicity and insulin resistance.[J].Jan F.C. Glatz;Yeliz Angin;Laura K.M. Steinbusch;Robert W. Schwenk;Joost J.F.P. Luiken.Prostaglandins; Leukotrienes and Essential Fatty Acids (PLEFA).2012,
[7]
Plasma levels of soluble CD36, platelet activation, inflammation, and oxidative stress are increased in type 2 diabetic patients [J].
Liani, Rossella ;
Halvorsen, Bente ;
Sestili, Simona ;
Handberg, Aase ;
Santilli, Francesca ;
Vazzana, Natale ;
Formoso, Gloria ;
Aukrust, Pal ;
Davi, Giovanni .
FREE RADICAL BIOLOGY AND MEDICINE, 2012, 52 (08) :1318-1324
[8]
Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population [J].
Handberg, A. ;
Hojlund, K. ;
Gastaldelli, A. ;
Flyvbjerg, A. ;
Dekker, J. M. ;
Petrie, J. ;
Piatti, P. ;
Beck-Nielsen, H. .
JOURNAL OF INTERNAL MEDICINE, 2012, 271 (03) :294-304
[9]
Fatty liver is associated with an increased risk of diabetes and cardiovascular disease - Evidence from three different disease models: NAFLD, HCV and HIV [J].
Lonardo, Amedeo ;
Ballestri, Stefano ;
Guaraldi, Giovanni ;
Nascimbeni, Fabio ;
Romagnoli, Dante ;
Zona, Stefano ;
Targher, Giovanni .
WORLD JOURNAL OF GASTROENTEROLOGY, 2016, 22 (44) :9674-9693
[10]
visfatin与2型糖尿病动脉粥样硬化关系研究进展 [J].
王艳 ;
王晶 ;
刘晓民 .
中华实用诊断与治疗杂志, 2016, 30 (08) :732-734