栀子苷治疗糖尿病及其并发症的分子机制研究进展

被引：19

作者：

朱迪娜 ^{[1
,2
]}

辛文锋 ^{[3
]}

张文生 ^{[1
,2
,3
]}

机构：

[1] 北京师范大学中药资源保护与利用北京市重点实验室

[2] 北京师范大学教育部天然药物工程研究中心

[3] 云南省三七生物技术与制药工程研究中心

来源：

环球中医药 | 2015年 / 8卷 / 05期

关键词：

糖尿病; 栀子苷; 京尼平; 分子机制;

D O I：

暂无

中图分类号：

R259 [现代医学内科疾病];

学科分类号：

100201 [内科学];

摘要：

糖尿病是一种以慢性高血糖为特征的代谢性疾病,可引起多种并发症,主要表现在全身微循环的障碍,如肾、眼、心血管及神经等慢性损伤。栀子苷是栀子的主要有效成分,其水解苷元为京尼平。有研究报道,栀子苷具有降低血糖,改善糖尿病并发症病理变化的作用,有望成为糖尿病治疗的潜在药物。本文对近年来栀子苷和京尼平治疗糖尿病的相关研究进行总结,以期为深入研究其治疗糖尿病的分子机制提供思路。

引用

页码：624 / 628

页数：5

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