肺部肿瘤合并轻度肺心病的临床诊治研究

被引：2

作者：

王晓宏 ^{[1
]}

谷平 ^{[1
,2
]}

机构：

[1] 本溪市中心医院呼吸科

[2] 本溪市中心医院心内科

来源：

现代肿瘤医学 | 2015年 / 23卷 / 18期

关键词：

肺部肿瘤; 轻度肺心病; CT灌注成像; 高射频; 放化疗; 临床疗效;

D O I：

暂无

中图分类号：

R734.2 [肺肿瘤]; R541.5 [肺原性心脏病];

学科分类号：

100214 ; 1002 ; 100201 ;

摘要：

目的:探讨肺部肿瘤合并轻度肺心病的临床诊断及治疗方法。方法:选择80例肺部肿瘤合并轻度肺心病患者,对所有患者进行多层螺旋CT灌注成像扫描,分析其临床数据。并观察同期60例正常人的右心室血流变化。将80例患者分为实验组和对照组,实验组患者行高射频(RFA)和放化疗综合治疗,对照组患者则单纯性放化疗治疗,所有患者均给予多巴酚丁胺和低分子肝素治疗,比较两组受试者3年的生存状况以及术后的并发症发生状况。结果:恶性肿瘤与良性肿瘤在局部血流量(BF)与对比剂平均通过时间(MTT)数据间无差异性(P>0.05),局部血容量(BV)与表面通透性(PS)差异有统计学意义(P<0.05)。以BV≤4ml/100g为诊断良性肿瘤的标准,诊断准确率为92.5%,误诊率为7.5%;以PS≥9ml/100g为诊断恶性肿瘤的标准,诊断正确率为90.0%,误诊率为10.0%。80例肺部肿瘤合并轻度肺心病患者肺动脉血流加速度(ACC)、最大肺动脉血流速度值(Vm)和右心室射血力(F)较正常对照组受试者差异有统计学意义(P<0.05)。实验组患者生存3年生存率高于对照组(P<0.05)。结论:CT灌注成像可提高肺部肿瘤的诊断准确率。合并轻度肺心病的患者肺动脉ACC、Vm和F值较正常人存在差异性。行RFA和放化疗综合治疗,能够显著提高患者的3年生存率,降低死亡率和复发率。

引用

页码：2597 / 2599

页数：3

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