CD105在恶性肿瘤诊断、预后及治疗中的意义

被引:4
作者
鹿群
机构
[1] 山东大学临床学院山东省立医院妇产科山东济南
关键词
CD105; 肿瘤; 诊断; 预后; 治疗;
D O I
暂无
中图分类号
R730.4 [肿瘤诊断学];
学科分类号
摘要
近年的研究表明 ,CD10 5是新生血管的标志 ,与肿瘤组织的浸润、转移有关。现综述CD10 5的结构、功能及其在恶性肿瘤的诊断、预后、生物治疗方面的作用。
引用
收藏
页码:358 / 360
页数:3
相关论文
共 17 条
  • [1] Elevated expression of endoglin, a component of the TGF-beta-receptor complex, correlates with proliferation of tumor endothelial cells. Miller DW,Graulich W,Karges B,et al. International Journal of Cancer . 1999
  • [2] Endoglin modulates cellular responses to TGF-beta 1. Lastres P,Letamendia A,Zhang H,et al. The Journal of Cell Biology . 1996
  • [3] Breast carcinoma: vascular density determined using CD105 antibody correlates with tumor prognosis. Kumar S,Ghellal A,Li C,et al. Cancer Research . 1999
  • [4] Endoglin: An accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies. Fonsatti E,Del Vecchio L,Altomonte M,et al. Journal of Cellular Physiology . 2001
  • [5] CD105 antagonizes the inhibitory signaling of transforming growth factor beta1 on human vascular endothelial cells. Li C,Hampson IN,Hampson L,et al. The FASEB Journal . 2000
  • [6] Defective angiogenesis in mice lacking endoglin. Li DY,Sorensen LK,Brooke BS,et al. Science . 1999
  • [7] Evaluation of angiogenesis in non-small cell lung cancer: comparison between anti-CD34 antibody and anti-CD105 antibody. Tanaka F,Otake Y,Yanagihara K,et al. Clinical Cancer Research . 2001
  • [8] Endoglin, a component of the TGF-beta receptor system, is a differentiation marker of human choriocarcinoma cells. Letamendia A,Lastres P,Almendro N,et al. International Journal of Cancer . 1998
  • [9] Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies. Matsuno F,Haruta Y,Kondo M,et al. Clinical Cancer Research . 1999
  • [10] Endoglin (CD105) expression in squamous cell carcinoma of the oral cavity. Schimming R,Marme D. Head and Neck . 2002