固相萃取技术在兽药残留分析中的应用

被引:14
作者
祝伟霞 [1 ]
杨冀州 [2 ]
梁炜 [2 ]
张书胜 [1 ]
机构
[1] 郑州大学化学系
[2] 河南出入境检验检疫局
关键词
固相萃取; 兽药残留; 分离模式;
D O I
10.16437/j.cnki.1007-5038.2007.08.026
中图分类号
S859.84 [动物性食品中化学物残留];
学科分类号
摘要
兽药残留不仅关系到食品安全,而且也影响国际贸易。固相萃取技术作为一种集富集净化于一体的净化方法具有简单、灵敏度高的特点,能有效去除复杂样品基质中干扰。近年来固相萃取技术在样品前处理中应用越来越广泛。文章根据不同的分离机理,分别论述了正相固相萃取、反相固相萃取、离子交换固相萃取、混合型固相萃取模式在样品净化过程中的作用原理,总结了不同理化性质目标化合物如何选择固相萃取,如何采用不同淋洗强度洗脱液及固相萃取在四环素类、2β-兴奋剂、磺胺类、硝基呋喃类等兽药残留中的应用。
引用
收藏
页码:99 / 101
页数:3
相关论文
共 9 条
  • [1] 固相萃取技术的发展与应用
    楼蔓藤
    商振华
    [J]. 分析仪器, 1998, (01) : 1 - 6
  • [2] 现代食品安全检测技术[M]. 科学出版社 , 唐英章, 2004
  • [3] Simultaneous extraction and analysis of 11 tetracycline and sulfonamide antibiotics in influent and effluent domestic wastewater by solid-phase extraction and liquid chromatography-electrospray ionization tandem mass spectrometry[J] . Shinwoo Yang,Jongmun Cha,Kenneth Carlson.Journal of Chromatography A . 2005 (1)
  • [4] A multi-residue cation-exchange clean up procedure for basic drugs in produce of animal origin
    Stubbings, G
    Tarbin, J
    Cooper, A
    Sharman, M
    Bigwood, T
    Robb, P
    [J]. ANALYTICA CHIMICA ACTA, 2005, 547 (02) : 262 - 268
  • [5] Simultaneous determination of 17 sulfonamide residues in porcine meat, kidney and liver by solid-phase extraction and liquid chromatography–tandem mass spectrometry[J] . Bing Shao,Dan Dong,Yongning Wu,Jianying Hu,Juan Meng,Xiaoming Tu,Shukun Xu.Analytica Chimica Acta . 2005 (2)
  • [6] Simultaneous extraction of tetracycline, macrolide and sulfonamide antibiotics from agricultural soils using pressurised liquid extraction, followed by solid-phase extraction and liquid chromatography–tandem mass spectrometry[J] . Journal of Chromatography A . 2004 (1)
  • [7] Identification of incurred sulfonamide residues in eggs: methods for confirmation by liquid chromatography–tandem mass spectrometry and quantitation by liquid chromatography with ultraviolet detection[J] . David N. Heller,Maureen A. Ngoh,Dan Donoghue,Lynda Podhorniak,Herbert Righter,Michael H. Thomas.Journal of Chromatography B . 2002 (1)
  • [8] Determination of antibiotics in different water compartments via liquid chromatography–electrospray tandem mass spectrometry[J] . Roman Hirsch,Thomas A Ternes,Klaus Haberer,Armin Mehlich,Frank Ballwanz,Karl-Ludwig Kratz.Journal of Chromatography A . 1998 (2)
  • [9] Simultaneous determination of anabolic steroids and synthetic hormones in meat by freezing lipid filtration,solid-phase extraction and gas chromatography mass spectrometry .2 Seoa J,Kima H.Y,Chungb B.C. J Chromatogr A . 2005