冠心病患者冠状动脉侧支循环形成的相关因素

被引:1
作者
许宜冠
周胜华
沈向前
祁述善
方臻飞
胡信群
机构
[1] 中南大学湘雅第二医院心血管内科
关键词
冠状动脉疾病; 冠状动脉侧支循环形成; 相关因素;
D O I
10.13191/j.chj.2005.04.54.xuyg.016
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
摘要
目的:探讨冠状动脉侧支循环形成的意义及影响侧支循环形成的相关因素。方法:冠状动脉造影中发现有侧支循环形成者47例作为研究组,以病变程度相同但无侧支循环形成者58例作为对照组;同时超声心动图检查病变局部室壁运动情况。结果:侧支循环形成与糖尿病、吸烟呈负相关,与服用他汀类药物呈正相关,而与性别、年龄、胸痛时间、有无高血压病、有无高脂血症、家族史、冠状动脉病变支数、服用ACEI类、硝酸酯类药物无关。结论:侧支循环多出现在病变严重的冠心病患者,糖尿病、吸烟是侧支循环形成的不利因素,服用他汀类药物能促进侧支循环形成;糖尿病患者即使形成侧支循环,对心功能的保护作用也较差。
引用
收藏
页码:356 / 358
页数:3
相关论文
共 7 条
[1]  
Coronary collateral circulation is less developed when ischaem ic heart disease coexistswith diabetes. Rzeczuch K,Jagielski D,Koloziej A,et al. KardiolPol . 2003
[2]  
Temporal evolution of the human coronary collateral circulation aftermyocardial infarction. SchwartzH,LeiboffRH,Bren GB,et al. Journal of the American College of Cardiology . 1984
[3]  
Collateral circulation in coronary artery disease. MacarthurA,V irendra SM,Robert JH,et al. The American Journal of Cardiology . 1985
[4]  
Angiotensin-converting enzyme inhibitor promotes coronary collateral circulation in patientswith coronary artery disease. M iura S,N ishikawa H,Zhang B,et al. C irc J . 2003
[5]  
Pravastatin promotes coronary collateral circulation in patients with coronary artery disease. N ishikawa H,M iura S,Zhang B,et al. Coronary Artery Disease . 2002
[6]  
Is there functional collateral flow during vascular coronary arteries?. Wustmann K,Zhinden S,W indecker S,et al. Circulation . 2003
[7]  
Frequency distribution of collateral flow and factors influencing collateral channel development. Tilmann P,Christian S,M ichael B,et al. Journal of the American College of Cardiology . 2001