慢性放射性肠炎的研究进展

被引：31

作者：

邱啸臣

张博

李元新

机构：

[1] 解放军医院普通外科

来源：

大连医科大学学报 | 2015年 / 37卷 / 03期

关键词：

慢性放射性肠炎; 放疗; 肠损伤;

D O I：

暂无

中图分类号：

R730.55 [放射疗法];

学科分类号：

100234 [放射肿瘤学];

摘要：

慢性放射性肠炎(CRE)是盆腔、腹腔、腹膜后恶性肿瘤经放射治疗引起的肠道并发症之一。CRE主要是由于电离产生的自由基对肠黏膜细胞的损伤导致的,造成的损伤主要包括:肠上皮细胞增生受抑制,肠黏膜下小动脉受损及肠壁组织慢性纤维化;CRE的临床表现为反复发作的便血、腹泻、腹痛,严重者出现肠梗阻、肠穿孔等,外科手术是CRE合并肠梗阻的最终治疗手段,本文就CRE的流行病学,发病机制及临床治疗的最新研究进展予以综述。

引用

页码：306 / 310

页数：5

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