环脂肽类成分研究进展

被引:11
作者
唐金山 [1 ]
高昊 [2 ]
戴毅 [2 ]
洪葵 [3 ]
姚新生 [1 ]
机构
[1] 沈阳药科大学中药学院
[2] 暨南大学中药及天然药物研究所
[3] 中国热带农业科学院热带作物生物技术国家重点实验室
关键词
微生物; 环脂肽; 化学成分; 生物活性; 结构鉴定;
D O I
10.16438/j.0513-4870.2008.09.006
中图分类号
R91 [药物基础科学];
学科分类号
1007 ;
摘要
环脂肽又名脂酰肽,是一类结构新颖的环状肽类化合物,具有抗菌、抗肿瘤、抗炎等广泛的生物活性,近年来受到人们的广泛关注。环脂肽类成分主要来源于微生物的次生代谢产物,包括蓝细菌(Cyanobacterium)、细菌(Bacterium)及放线菌等微生物,其中海洋细菌主要包括芽胞杆菌属(Bacillus)和假单胞菌属(Pseudomonas)。本文拟就近年来环脂肽类成分研究进展进行综述。
引用
收藏
页码:873 / 883
页数:11
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