扩张型心肌病与心肌自身抗体的研究进展

被引:13
作者
张群燕
蔡辉
机构
[1] 南京军区南京总医院中西医结合科
关键词
心肌病,扩张型; 心肌细胞; 自身抗体;
D O I
10.13191/j.chj.2010.02.114.zhangqy.016
中图分类号
R542.2 [心肌疾病];
学科分类号
100201 [内科学];
摘要
近年来,随着免疫学、病毒学、分子生物学理论与技术的发展,抗心肌抗体与扩张型心肌病(DCM)的关系越来越受重视。抗心肌抗体的产生和参与DCM的资料累积已近50年。例如抗β肾上腺能受体抗体、抗ATP/ADP运载蛋白抗体、抗M胆碱能受体抗体和抗肌球蛋白重链抗体等,均可激活机体免疫系统使心肌细胞肿胀和坏死,是心脏受累的重要指标。本文主要对DCM与心肌自身抗体的相关发病机制作一综述。
引用
收藏
页码:264 / 266
页数:3
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