年轻乳腺癌患者诊疗进展

被引:17
作者
汤立晨 [1 ,2 ]
狄根红 [1 ,2 ]
邵志敏 [1 ,2 ]
机构
[1] 复旦大学附属肿瘤医院乳腺外科
[2] 复旦大学上海医学院肿瘤学系
关键词
年轻乳腺癌; 诊断; 特征; 治疗;
D O I
10.16073/j.cnki.cjcpt.2009.17.025
中图分类号
R737.9 [乳腺肿瘤];
学科分类号
100214 ;
摘要
目的:总结年轻乳腺癌患者的临床病理特征、早期诊断方法、综合治疗获益及化疗后保留生育功能的研究进展。方法:以"年轻乳腺癌,特征,诊断和治疗"为关键词,检索Medline及中文全文期刊数据库1990-01-2008-12的相关文献,获得英文文献2664篇,中文文献121篇。纳入标准:1)年轻乳腺癌患者临床及病理特征;2)年轻乳腺癌患者诊断方法;3)年轻乳腺癌患者综合治疗获益;4)年轻乳腺癌患者化疗后闭经及生育功能的保留。根据纳入标准精选72篇文献,最后纳入分析42篇文献。结果:年轻乳腺癌患者较年长者具有更多不良预后特征。随着综合治疗手段的进步,年轻的乳腺癌患者有了更多综合治疗的选择,但疗效尚未确定。对于化疗后闭经的年轻患者,其生育功能的保留从技术上是可行的。结论:年轻乳腺癌患者具有不良的预后特征,相对年长乳腺癌患者预后较差。针对年轻乳腺癌患者的循证医学证据尚不充分,其定义、诊疗规范还有待于进一步循证以达成共识。
引用
收藏
页码:1351 / 1354
页数:4
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