HPV致宫颈癌分子机理研究

被引:4
作者
韩苏夏
机构
[1] 西安交通大学第一医院肿瘤科
关键词
HPV; 宫颈癌; HLA; 细胞周期; 抑癌基因;
D O I
暂无
中图分类号
R737.33 [子宫肿瘤];
学科分类号
100214 ;
摘要
宫颈癌是仅次于乳腺癌而引起妇女癌症相关死亡的重要原因 ,目前认为人乳头瘤病毒(HPV)是宫颈癌的主要致病因子。该文对HPV基因组特征与宫颈癌的易感性 ,宿主感染后HPV影响机体组织人白细胞抗原 (HLA)分子表达 ,逃脱免疫监视 ,降解 p5 3,使 pRb失活 ,下调抑癌基因p2 1、p2 7表达等而导致宫颈癌的相关分子机理研究进行综述
引用
收藏
页码:20 / 22
页数:3
相关论文
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