幽门螺杆菌疫苗的研究进展

被引：16

作者：

邹全明

机构：

[1] 第三军医大学临床微生物学及免疫学教研室重庆市生物制药工程技术研究中心

来源：

胃肠病学 | 2007年 / 09期

关键词：

螺杆菌，幽门; 疫苗; 进展;

D O I：

暂无

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

幽门螺杆菌(H.pylori)是人类上消化道疾病的重要致病菌,为慢性胃炎、胃溃疡和十二指肠溃疡的主要病因。目前临床治疗尚存在诸多不足,研制疫苗对预防和控制H.pylori感染具有十分重要的意义。经过20余年的发展,H.pylori疫苗在动物模型建立、候选抗原的选择、佐剂和投递方式的优化等方面均已取得了较大突破。本文主要就全菌疫苗、亚单位疫苗(基因工程疫苗)、活载体疫苗和DNA疫苗四种类型的H.pylori疫苗的研究现状作一概述。

引用

页码：567 / 570

页数：4

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