镉与氧化损伤研究进展

被引:20
作者
洪峰
机构
[1] 复旦大学公共卫生学院劳动卫生教研室上海
关键词
镉; 氧化损伤; 进展;
D O I
暂无
中图分类号
R114 [卫生毒理];
学科分类号
100405 ;
摘要
镉普遍存在于自然界 ,急性和亚慢性接触镉会导致人类和动物的多系统损害。镉的毒性与细胞脂质过氧化密切相关 ,镉可诱发细胞内脂质过氧化物生成 ,而细胞氧化还原过程的平衡取决于复杂的酶和非酶性抗氧化防御系统。从镉诱导氧化损伤的启动、镉与抗氧化系统、氧化损伤与凋亡、镉耐受以及镉毒性的预防等方面对镉的氧化损伤作用作一评述。并对目前镉健康效应的进一步研究提出建议。
引用
收藏
页码:97 / 103
页数:7
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