食管鳞癌中CD44v4/5、MMP-10的表达与淋巴结转移的关系

被引：3

作者：

王毅

赵国昌

李汉臣

机构：

[1] 新乡医学院第一附属医院胸外科

来源：

医学信息(手术学分册) | 2008年 / 08期

关键词：

食管鳞癌; CD44v4/5; MMP-10; 淋巴结转移;

D O I：

暂无

中图分类号：

R735.1 [食管肿瘤];

学科分类号：

摘要：

目的研究食管鳞癌中CD44v4/5、MMP-10的表达与浸润转移的关系。方法用免疫组化S-P法检测了73例食管鳞癌中CD44v4/5、MMP-10的表达。结果CD44v4/5在淋巴结转移组的阳性表达率为64.6%(31/48),而在非转移组的阳性表达率为32.0%(8/25),两组之间差异显著(P<0.05)。MMP-10在淋巴结转移组的阳性表达率为79.2%(38/48),而在非转移组阳性表达率为40.0%(10/25),两组之间亦具有显著差异(P<0.05)。结论CD44v4/5和MMP-10的表达均与食管鳞癌浸润密切相关。

引用

页码：731 / 732+742 +742

页数：3

共 15 条

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