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水通道蛋白5在人胎肺发育中的表达及意义
被引:10
作者
:
牛惠惠
论文数:
0
引用数:
0
h-index:
0
机构:
华中科技大学同济医学院附属同济医院妇产科
牛惠惠
曾万江
论文数:
0
引用数:
0
h-index:
0
机构:
华中科技大学同济医学院附属同济医院妇产科
曾万江
机构
:
[1]
华中科技大学同济医学院附属同济医院妇产科
来源
:
中国优生与遗传杂志
|
2010年
/ 18卷
/ 04期
关键词
:
水通道蛋白5;
胎肺发育;
肺泡Ⅰ型上皮细胞;
D O I
:
10.13404/j.cnki.cjbhh.2010.04.003
中图分类号
:
R321.54 [];
学科分类号
:
摘要
:
目的检测水通道蛋白5(AQP5)在胎儿正常肺组织和发育异常肺组织的表达,探讨AQP5对胎肺发育的影响及其在肺液代谢中的作用。方法应用RT-PCR检测AQP5mRNA在各胎肺中的表达以及real-timePCR检测AQP5在正常胎肺和发育异常胎肺中的基因表达差异。结果AQP5mRNA在各孕周胎肺均有表达,发育异常胎肺组织较正常胎肺组织表达量明显减少,差异有统计学意义(P<0.05))。结论发育异常胎肺AQP5表达下降,其对胎肺的正常发育和肺液代谢可能有重要影响。
引用
收藏
页码:75 / 76+25 +25
页数:3
相关论文
共 4 条
[1]
水通道蛋白1,5与新生鼠高氧肺损伤肺水肿的关系研究
[J].
岳冬梅
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0
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中国医科大学附属第二临床学院儿科
岳冬梅
;
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薛辛东
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中国当代儿科杂志,
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Impaired alveolar epithelial cell differentiation in the hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia
[J].
Takayasu, Hajime
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Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
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Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
Puri, Prem
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PEDIATRIC SURGERY INTERNATIONAL,
2007,
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(05)
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Diversity of aquaporin mRNA expressed by rat and human retinas
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Tenckhoff, S
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Univ Leipzig, Fac Med, Dept Ophthalmol, D-04103 Leipzig, Germany
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Univ Leipzig, Fac Med, Dept Ophthalmol, D-04103 Leipzig, Germany
Kohen, L
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Identification of two novel markers for alveolar epithelial type I and II cells
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Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
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Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
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Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
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Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
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Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Liu, L
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,
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←
1
→
共 4 条
[1]
水通道蛋白1,5与新生鼠高氧肺损伤肺水肿的关系研究
[J].
岳冬梅
论文数:
0
引用数:
0
h-index:
0
机构:
中国医科大学附属第二临床学院儿科
岳冬梅
;
论文数:
引用数:
h-index:
机构:
薛辛东
.
中国当代儿科杂志,
2006,
(02)
:147
-150
[2]
Impaired alveolar epithelial cell differentiation in the hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia
[J].
Takayasu, Hajime
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
Takayasu, Hajime
;
Nakazawa, Nana
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
Nakazawa, Nana
;
Montedonico, Sandra
论文数:
0
引用数:
0
h-index:
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Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
Montedonico, Sandra
;
Sugimoto, Kaoru
论文数:
0
引用数:
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h-index:
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Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
Sugimoto, Kaoru
;
Sato, Hideaki
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0
引用数:
0
h-index:
0
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Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
Sato, Hideaki
;
Puri, Prem
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
Univ Coll Dublin, Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
Puri, Prem
.
PEDIATRIC SURGERY INTERNATIONAL,
2007,
23
(05)
:405
-410
[3]
Diversity of aquaporin mRNA expressed by rat and human retinas
[J].
Tenckhoff, S
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Leipzig, Fac Med, Dept Ophthalmol, D-04103 Leipzig, Germany
Tenckhoff, S
;
Hollborn, M
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Leipzig, Fac Med, Dept Ophthalmol, D-04103 Leipzig, Germany
Hollborn, M
;
Kohen, L
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Leipzig, Fac Med, Dept Ophthalmol, D-04103 Leipzig, Germany
Kohen, L
;
Wolf, S
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Leipzig, Fac Med, Dept Ophthalmol, D-04103 Leipzig, Germany
Wolf, S
;
Wiedemann, P
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Leipzig, Fac Med, Dept Ophthalmol, D-04103 Leipzig, Germany
Wiedemann, P
;
Bringmann, A
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Leipzig, Fac Med, Dept Ophthalmol, D-04103 Leipzig, Germany
Bringmann, A
.
NEUROREPORT,
2005,
16
(01)
:53
-56
[4]
Identification of two novel markers for alveolar epithelial type I and II cells
[J].
Chen, ZM
论文数:
0
引用数:
0
h-index:
0
机构:
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Chen, ZM
;
Jin, NL
论文数:
0
引用数:
0
h-index:
0
机构:
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Jin, NL
;
Narasaraju, T
论文数:
0
引用数:
0
h-index:
0
机构:
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Narasaraju, T
;
Chen, JW
论文数:
0
引用数:
0
h-index:
0
机构:
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Chen, JW
;
McFarland, LR
论文数:
0
引用数:
0
h-index:
0
机构:
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
McFarland, LR
;
Scott, M
论文数:
0
引用数:
0
h-index:
0
机构:
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Scott, M
;
Liu, L
论文数:
0
引用数:
0
h-index:
0
机构:
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Oklahoma State Univ, Dept Physiol Sci, Stillwater, OK 74078 USA
Liu, L
.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,
2004,
319
(03)
:774
-780
←
1
→