瘦素与葡萄糖代谢的关系

被引:16
作者
李剑
陆菊明
潘长玉
机构
[1] 解放军总医院内分泌科!北京
关键词
瘦素; 葡萄糖代谢; 肥胖; 胰岛素抵抗;
D O I
暂无
中图分类号
R392.1 [免疫生物学];
学科分类号
摘要
瘦素为脂肪细胞分泌的保持机体能量平衡的激素。瘦素受体的分布广泛 ,瘦素通过中枢神经系统调节能量代谢 ,也有广泛的周围作用 ,通过胰腺、肝脏、骨骼肌等发挥其作用。瘦素对葡萄糖的产生、转运、代谢及脂肪的分解合成有影响 ,并且作用于其它影响能量代谢的因子 ,直接或间接地影响能量平衡。瘦素和受体的作用障碍 ,可导致肥胖、胰岛素抵抗等能量代谢异常
引用
收藏
页码:314 / 317
页数:4
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