Klebsiella pneumoniae合成1,3-丙二醇过程中的生长与催化耦联

被引：11

作者：

杜晨宇

李春

杨东

张延平

曹竹安

机构：

[1] 清华大学化学工程系生物化工研究所

[2] 清华大学化学工程系生物化工研究所北京

[3] 北京

来源：

化工学报 | 2004年 / 03期

基金：

国家科技攻关计划;

关键词：

生长与催化耦联; Klebsiella pneumoniae; 1,3-丙二醇; 甘油;

D O I：

暂无

中图分类号：

TQ922 [发酵法制氨基酸];

学科分类号：

081703 ; 082203 ;

摘要：

This paper focuses on the research of the bioconversion of 1,3-propanediol by Klebsiella pneumoniae. The linear correlation of cell growth and 1,3-propanediol synthesis was found. An equation of the relationship between cell growth and biocatalysis was given.With the analysis of metabolism, it was discovered that the cell regulated the NADH production by cell growth in order to supply enough reductive equivalent for enzyme catalysis. A conclusion was drawn that the cell growth was coupled with the reactivation of a key-enzyme which catalyzes 1,3-propanediol production in Klebsiella pneumoniae.

引用

页码：505 / 508

页数：4

共 7 条

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[2]

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[7]

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