性激素结合球蛋白与胰岛素抵抗相关性疾病关系的研究进展

被引:20
作者
刘英
江霞
机构
[1] 天津市第一中心医院
关键词
性激素结合球蛋白; 胰岛素抵抗; 糖尿病; 高尿酸血症; 非酒精性脂肪肝; 肿瘤;
D O I
暂无
中图分类号
R363 [病理生理学];
学科分类号
100103 [病原生物学];
摘要
性激素结合球蛋白(SHBG)是来源于肝脏的一种结合性激素的糖蛋白,不仅是一种运载蛋白,而且还具有激素样作用,与受体结合后可参与类固醇激素的信号转导过程。研究证实血浆SHBG水平与机体胰岛素抵抗(IR)程度有关,并参与2型糖尿病、妊娠期糖尿病、多囊卵巢综合征、高尿酸血症、非酒精性脂肪肝、肥胖、肿瘤等IR相关性疾病的发生。
引用
收藏
页码:105 / 107
页数:3
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