幽门螺杆菌与胃食管反流病

被引：5

作者：

赵晶京

房殿春

机构：

[1] 重庆西南医院全军消化病研究所

来源：

胃肠病学和肝病学杂志 | 2008年 / 07期

关键词：

幽门螺杆菌; 胃食管反流病;

D O I：

暂无

中图分类号：

R571 [食管疾病];

学科分类号：

100201 [内科学];

摘要：

幽门螺杆菌(Helicobacter pylori,H.pylori)与胃食管反流病(gastroesophageal reflux disease,GERD)的关系各研究结果不尽一致,流行病学研究表明,在GERD中不仅H.pylori感染率较低,而且cagA的检出率也低,二者都与食管疾病严重程度呈负相关。亦有文献报告H.pylori感染与GERD发生无明显关系。H.pylori对食管保护作用机制可能与其能提高LES压力、降低胃内酸度和影响食管对酸的敏感性有关。有研究表明,H.pylori可以提高质子泵抑制剂的抑酸效果,亦有人认为H.pylori并不影响GERD疗效。因此H.pylori与GERD的关系仍需进一步的临床和基础研究来评价。

引用

收藏

页码：519 / 522

页数：4

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