隐匿性乙型肝炎研究现状

被引:10
作者
史宇晖
庄辉
机构
[1] 北京大学医学部微生物学系
关键词
隐匿性乙型肝炎; 特异度; HBVDNA; HBsAg;
D O I
暂无
中图分类号
R512.6 [病毒性肝炎];
学科分类号
100401 ;
摘要
<正> 乙型肝炎病毒(HBV)感染是一个严重的全球性问题,我国是 HBV 的高感染地区,约1.2亿人携带 HBV,其中约1/4的人最终将发展为慢性肝病,包括肝硬化和肝癌。慢性 HBV感染是我国肝硬化和肝癌的最主要病因,严重威胁人民健康,也给国家带来巨大的经济损失。多数 HBV 感染无明显临床症状,血清 HBV 表面抗原(HBsAg)阳性和病毒血症是 HBV 感染的主要证据。血清 HBsAg 阴转及抗 HBs 的出现一直被认为是 HBV 清除和临床痊愈的标志。1978年 Hoofnagle 等报道:HBsAg 和抗 HBs 阴性,但抗HBc 阳性的血液可引起输血后 HBV 感染,提示单独抗 HBc
引用
收藏
页码:97 / 99
页数:3
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